Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027105 | 1.00 | KMT2A (0.38) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6027478 | 1.00 | KMT2A (0.38) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6467655 | 1.00 | KMT2A (0.38) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6026767 | 0.91 | KMT2A (0.45) | KMT2ASTING1PDE4DPDE4APDE4B | |
| SCHEMBL6026232 | 0.89 | STING1 (0.40) | KMT2ASTING1MTNR1AMTNR1BLMNA | |
| SCHEMBL4770361 | 0.88 | PIK3CD (0.47) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6025152 | 0.88 | KMT2A (0.47) | KMT2ASTING1PDE4DPDE4APDE4B | |
| SCHEMBL6026200 | 0.88 | KMT2A (0.47) | KMT2ASTING1PDE4DPDE4APDE4B | |
| SCHEMBL6026496 | 0.87 | PIK3CD (0.36) | KMT2ASTING1PIK3CDGAATSHR | |
| SCHEMBL6020509 | 0.85 | STING1 (0.42) | KMT2ASTING1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096350-A1 | Halo substituted benzo[b]thiophenes as therapeutic agents | CONNOLLY MICHAEL K (US) | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096350-A1 | Halo substituted benzo[b]thiophenes as therapeutic agents | HCLS1, BRI3BP, BRPF1 | KMT2A 3608/4885STING1 2297/4885PIK3CD 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.