Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468691 | 0.80 | RXFP1 (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19RXFP1 | |
| SCHEMBL3790456 | 0.78 | ADORA2A (0.63) | CYP1A2CYP3A4CYP2C9CYP2C19ADORA2A | |
| SCHEMBL4458405 | 0.77 | ADORA2A (0.67) | RXFP1RPS6KA5ADORA2AADORA2BADORA1 | |
| SCHEMBL29878888 | 0.76 | RXFP1 (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19RXFP1 | |
| SCHEMBL28850551 | 0.76 | RXFP1 (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19RXFP1 | |
| SCHEMBL7894650 | 0.76 | PSEN1 (0.44) | CYP3A4CYP2C9CYP2C19RXFP1RPS6KA5 | |
| SCHEMBL14685153 | 0.74 | TLR7 (0.48) | RXFP1RPS6KA5ADORA2AADORA2BADORA1 | |
| SCHEMBL24401874 | 0.73 | KDM4E (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19ADORA2A | |
| SCHEMBL4454549 | 0.73 | NOTUM (0.40) | CYP1A2CYP2C9CYP2C19RXFP1RPS6KA5 | |
| SCHEMBL3295739 | 0.72 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060194782-A1 | Pharmacologically active imidazo[4,5-c] pyridines | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
| EP-1670795-A1 | PHARMACOLOGICALLY ACTIVE IMIDAZO 4,5-C PYRIDINES | ALTANA Pharma AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005026164-A1 | PHARMACOLOGICALLY ACTIVE IMIDAZO[4,5-C]PYRIDINES | ALTANA PHARMA AG (DE) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194782-A1 | Pharmacologically active imidazo[4,5-c] pyridines | GIPR, VIP, PGC | CYP1A2 216/4885CYP3A4 29/4885CYP2C9 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.