⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17336797 | 0.81 | — | — | |
| SCHEMBL30679595 | 0.80 | CYP4F2 (0.33) | — | |
| SCHEMBL8930843 | 0.79 | — | — | |
| SCHEMBL8524508 | 0.79 | — | — | |
| SCHEMBL28026136 | 0.79 | — | — | |
| SCHEMBL8759360 | 0.78 | — | — | |
| SCHEMBL5820520 | 0.77 | HSD11B1 (0.31) | — | |
| SCHEMBL5923548 | 0.77 | HSD11B1 (0.31) | — | |
| SCHEMBL29412238 | 0.76 | — | — | |
| SCHEMBL29412235 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667965-A2 | BRIDGED MACROCYCLIC MODULE COMPOSITIONS | Covalent Partners, LLC (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030711-A2 | BRIDGED MACROCYCLIC MODULE COMPOSITIONS | COVALENT PARTNERS LLC (US) | 2005-04-07 | — | — | WO | disclosed |
| US-4446224-A | DIOL, REDUCING AGENT, MATRIX | ENERGY CONVERSION DEVICES, INC. (US) | 1984-05-01 | — | — | US | disclosed |
| EP-0099146-A2 | Film and composition for forming an image and method for recording electromagnetic radiation | ENERGY CONVERSION DEVICES, INC. (US) | 1984-01-25 | — | — | EP | disclosed |