Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 4/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NCK1 | P16333 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241793 | 0.76 | NQO2 (0.64) | NQO2KDM4EMAPTNCK1BACE1 | |
| SCHEMBL8749414 | 0.75 | NQO2 (0.52) | NQO2KDM4EMAPTNCK1BACE1 | |
| SCHEMBL5997520 | 0.75 | PIK3CG (0.85) | PDPK1SRCPIK3CGPABPC1KDM4E | |
| SCHEMBL5995514 | 0.75 | PDPK1 (0.54) | PDPK1SRCPIK3CGPABPC1KDM4E | |
| SCHEMBL18873137 | 0.75 | NQO2 (0.57) | NQO2KDM4EMAPTNCK1BACE1 | |
| SCHEMBL30745612 | 0.75 | NQO2 (0.70) | NQO2KDM4EMAPTNCK1BACE1 | |
| SCHEMBL434975 | 0.75 | NQO2 (0.70) | NQO2KDM4EMAPTNCK1BACE1 | |
| SCHEMBL5995026 | 0.75 | MEN1 (0.56) | PDPK1NQO2SRCPIK3CGPABPC1 | |
| SCHEMBL15095319 | 0.75 | PIK3CG (0.46) | PDPK1SRCPIK3CGPABPC1NCK1 | |
| SCHEMBL2756741 | 0.74 | NQO2 (0.85) | NQO2KDM4EMAPTNCK1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723125-A1 | NOVEL 1,2,4-BENZOTRIAZINE-1,4-DIOXIDES | Auckland Uniservices Limited (NZ) | 2006-11-22 | — | — | EP | claimed |
| WO-2005082867-A1 | NOVEL 1,2,4-BENZOTRIAZINE-1,4-DIOXIDES | AUCKLAND UNISERVICES LIMITED (NZ) | 2005-09-09 | — | — | WO | claimed |
| EP-1723125-A1 | NOVEL 1,2,4-BENZOTRIAZINE-1,4-DIOXIDES | Auckland Uniservices Limited (NZ) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005082867-A1 | NOVEL 1,2,4-BENZOTRIAZINE-1,4-DIOXIDES | AUCKLAND UNISERVICES LIMITED (NZ) | 2005-09-09 | — | — | WO | disclosed |