Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.85 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366137 | 0.92 | PIK3CG (1.00) | PIK3CGPDPK1PABPC1MAPTKDM4E | |
| SCHEMBL11723768 | 0.76 | PIK3CG (0.61) | PIK3CGMAPTKDM4EMEN1USP2 | |
| SCHEMBL5995514 | 0.75 | PDPK1 (0.54) | PIK3CGPDPK1PABPC1MAPTKDM4E | |
| SCHEMBL8401963 | 0.75 | PIK3CG (0.50) | PIK3CGMAPTKDM4EMEN1USP2 | |
| SCHEMBL6028146 | 0.75 | PDPK1 (0.54) | PIK3CGPDPK1PABPC1MAPTKDM4E | |
| SCHEMBL5157381 | 0.74 | PIK3CG (0.58) | PIK3CGMAPTKDM4EMEN1USP2 | |
| SCHEMBL14166725 | 0.74 | MAPT (0.60) | PIK3CGMAPTKDM4EMEN1USP2 | |
| SCHEMBL2821331 | 0.71 | KMT2A (0.69) | PIK3CGMAPTKDM4EMEN1USP2 | |
| SCHEMBL1138685 | 0.71 | PIK3CG (0.55) | PIK3CGMAPTKDM4EMEN1USP2 | |
| SCHEMBL5995026 | 0.71 | MEN1 (0.56) | PIK3CGPDPK1PABPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129349-B2 | Methods of synthesizing 3-amino-1,2,4-benzotriazines | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2006-10-31 | — | — | US | disclosed |
| US-20060142569-A1 | Methods of synthesizing 3-amino-1,2-4-benzotriazines | TRUSTEES OF DARTMOUTH COLLEGE | 2006-06-29 | — | — | US | disclosed |
| WO-2004034023-A2 | METHODS OF SYNTHESIZING 3-AMINO-1,2,4-BENZOTRIAZINES | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142569-A1 | Methods of synthesizing 3-amino-1,2-4-benzotriazines | GNMT, GLB1, GNB1 | PIK3CG 2487/4885PDPK1 4104/4885PABPC1 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.