Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622853 | 1.00 | KDM4E (0.50) | KDM4ELCKALDH1A1POLBSLC17A5 | |
| SCHEMBL5623505 | 1.00 | KDM4E (0.50) | KDM4ELCKALDH1A1POLBSLC17A5 | |
| SCHEMBL5622593 | 0.88 | SLC17A5 (0.60) | KDM4ELCKALDH1A1POLBSLC17A5 | |
| SCHEMBL5623603 | 0.85 | KDM4E (0.55) | KDM4ELCKALDH1A1POLBHPGD | |
| SCHEMBL5622981 | 0.80 | KDM4E (0.58) | KDM4ELCKALDH1A1POLBHPGD | |
| SCHEMBL5622471 | 0.79 | SLC17A5 (0.64) | KDM4ELCKALDH1A1POLBSLC17A5 | |
| SCHEMBL5276812 | 0.79 | SLC17A5 (0.64) | KDM4ELCKALDH1A1POLBSLC17A5 | |
| SCHEMBL5622852 | 0.79 | SLC17A5 (0.64) | KDM4ELCKALDH1A1POLBSLC17A5 | |
| SCHEMBL1311053 | 0.78 | FABP5 (0.44) | ALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31665940 | 0.75 | MDM2 (0.38) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711483-A2 | A METHOD FOR MANUFACTURING OPTICALLY PURE COUMARYL AMINO ACID SALTS AND THE COUMARYL AMINO ACID SALTS THUS OBTAINED | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005075448-A2 | A METHOD FOR MANUFACTURING OPTICALLY PURE COUMARYL AMINO ACIDS SALTS AND THE COUMARYL AMINO ACID SALTS THUS OBTAINED | INSTITUT NATIONAL DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-08-18 | — | — | WO | disclosed |