Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264305 | 0.89 | SMN1; SMN2 (0.55) | FABP5SMN1; SMN2HIF1AKMT2AFABP7 | |
| SCHEMBL27522574 | 0.89 | SMN1; SMN2 (0.55) | FABP5SMN1; SMN2HIF1AKMT2AFABP7 | |
| SCHEMBL29019464 | 0.89 | SMN1; SMN2 (0.55) | FABP5SMN1; SMN2HIF1AKMT2AFABP7 | |
| SCHEMBL28356620 | 0.89 | SMN1; SMN2 (0.42) | FABP5SMN1; SMN2HIF1AMDM2KMT2A | |
| SCHEMBL29019459 | 0.89 | SMN1; SMN2 (0.42) | FABP5SMN1; SMN2HIF1AMDM2KMT2A | |
| SCHEMBL29019435 | 0.89 | SMN1; SMN2 (0.42) | FABP5SMN1; SMN2HIF1AMDM2KMT2A | |
| SCHEMBL31665940 | 0.87 | MDM2 (0.38) | FABP5SMN1; SMN2HIF1AMDM2KMT2A | |
| SCHEMBL28884665 | 0.87 | SMN1; SMN2 (0.45) | FABP5SMN1; SMN2HIF1AKMT2AFABP7 | |
| SCHEMBL28884667 | 0.87 | SMN1; SMN2 (0.45) | FABP5SMN1; SMN2HIF1AKMT2AFABP7 | |
| SCHEMBL16634841 | 0.86 | SMN1; SMN2 (0.46) | FABP5SMN1; SMN2HIF1AMDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877968-B2 | Melanocortin receptor modulators, process for preparing them and use there in human medicine and cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-11-04 | — | — | US | disclosed |
| EP-2352728-B1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RES & DEV (FR) | 2014-05-21 | — | — | EP | disclosed |
| US-20110275657-A1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THERE IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275657-A1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THERE IN HUMAN MEDICINE AND COSMETICS | MC1R, MC5R, MC3R | FABP5 882/4885SMN1; SMN2 4580/4885HIF1A 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.