Ascorbic Acid

Ascorbic Acid

SCHEMBL6028836

O=C1OC([C@H](O)CO)C(O)=C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
LMNA P02545 2/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
HSPD1 P10809 1/20 0.51
HSPE1 P61604 1/20 0.51
TST Q16762 1/20 0.51
RECQL P46063 1/20 0.51
BLM P54132 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
TYR P14679 2/20 0.45
MANBA O00462 1/20 0.39
THRB P10828 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ascorbic Acid SCHEMBL31676316 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL2564750 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL10957988 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL18678 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL786 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL785 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL734589 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL11981759 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL21114349 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL30704238 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3199536-B1 PREPARATION METHOD FOR BENZOXAZOLEOXAZINE KETONE COMPOUND AND INTERMEDIATE AND CRYSTAL FORM THEREOF NORTH CHINA PHARMACEUTICAL NEW DRUG R&D CO LTD (DE) 2020-06-10 EP disclosed
EP-3646770-A1 ENDOSCOPE FLEXIBLE TUBE, ENDOSCOPE-TYPE MEDICAL DEVICE, RESIN COMPOSITION FOR COATING ENDOSCOPE FLEXIBLE-TUBE SUBSTRATE, AND RESIN COMPOSITION SET FOR COATING ENDOSCOPE FLEXIBLE-TUBE SUBSTRATE FUJIFILM Corporation (JP) 2020-05-06 EP disclosed
US-20170275299-A1 PREPARATION METHOD FOR BENZOXAZOLEOXAZINE KETONE COMPOUND AND INTERMEDIATE AND CRYSTAL FORM THEREOF NORTH CHINA PHARMACEUTICAL NEW DRUG R&D CO., LTD. (CN) 2017-09-28 US disclosed
US-20170275299-A1 PREPARATION METHOD FOR BENZOXAZOLEOXAZINE KETONE COMPOUND AND INTERMEDIATE AND CRYSTAL FORM THEREOF NORTH CHINA PHARMACEUTICAL NEW DRUG R&D CO., LTD. (CN) 2017-09-28 US disclosed
EP-3199536-A1 PREPARATION METHOD FOR BENZOXAZOLEOXAZINE KETONE COMPOUND AND INTERMEDIATE AND CRYSTAL FORM THEREOF North China Pharmaceutical New Drug R&D Co., Ltd. (DE) 2017-08-02 EP disclosed
EP-1592837-B1 NON-YELLOWING ALDEHYDE CONDENSATION PRODUCTS CLARIANT FINANCE BVI LTD (VG) 2013-04-03 EP disclosed
US-20060134446-A1 Non-yellowing aldehyde condensation products CLARIANT FINANCE (BVI) LIMITED (VG) 2006-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170275299-A1 PREPARATION METHOD FOR BENZOXAZOLEOXAZINE KETONE COMPOUND AND INTERMEDIATE AND CRYSTAL FORM THEREOF CYP4F11, CYP51A1, CYP2F1 MAPT 1877/4885LMNA 1235/4885L3MBTL1 4245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.