Ascorbic Acid

Ascorbic Acid

SCHEMBL785

O=C1O[C@H]([C@@H](O)CO)C(O)=C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
LMNA P02545 2/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
HSPD1 P10809 1/20 0.51
HSPE1 P61604 1/20 0.51
TST Q16762 1/20 0.51
RECQL P46063 1/20 0.51
BLM P54132 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
TYR P14679 2/20 0.45
MANBA O00462 1/20 0.39
THRB P10828 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ascorbic Acid SCHEMBL31676316 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL2564750 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL6028836 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL10957988 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL18678 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL786 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL734589 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL11981759 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL21114349 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL30704238 1.00 MAPT (1.00) MAPTLMNAL3MBTL1HSPD1HSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 1232293 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372755-B1 None US claimed
US-6423298-B1 None US claimed
US-9974693-B2 Devices, systems, and methods for instillation of foamed fluid with negative pressure wound therapy KCI LICENSING, INC. (US) 2018-05-22 US claimed
US-9974859-B2 Nanostructured gels capable of controlled release of entrapped agents THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2018-05-22 US claimed
US-9975915-B1 Crystalline forms of nicotinoyl ribosides, modified derivatives thereof, and phosphorylated analogs thereof, and methods of preparation thereof THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2018-05-22 US claimed
US-9976111-B2 TiN hard mask and etch residual removal VERSUM MATERIALS US, LLC (US) 2018-05-22 US claimed
US-20180134888-A1 ULTRA-HIGH SOLIDS EMULSION AND APPLICATION HERCULES LLC (DE) 2018-05-17 US claimed
US-20180133273-A1 Use of Ginseng Extract, Ginsenoside and Ginsenoside Derivative in the Preparation of Medicine or Health Care Product for Treating Cytomegalovirus Infection Disorders FU, LI (CN) 2018-05-17 US claimed
US-20180134742-A1 CRYSTALLINE FORMS OF NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, AND PHOSPHORYLATED ANALOGS THEREOF, AND METHODS OF PREPARATION THEREOF THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2018-05-17 US claimed
US-20180133318-A1 ENHANCED PLASMONIC NANOPARTICLES FOR CANCER THERAPY AND DIAGNOSTICS BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2018-05-17 US claimed
US-3956476-A X-RAYS, MEDICAL DIAGNOSIS SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) 1976-05-11 US claimed
US-3954999-A OXIDIZERS, HYDRATED SALT, FLOUR PENNWALT CORPORATION (US) 1976-05-04 US claimed
US-3954724-A ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-04 US claimed
US-3950133-A POLYOXYALKYLENE, CATALYST MALLINCKRODT, INC. (US) 1976-04-13 US claimed
US-3950290-A DISPERSION, WATER SOLUBLE OILS, STYRENE POLYMERS A. E. STALEY MANUFACTURING COMPANY (US) 1976-04-13 US claimed
US-3947500-A Process for treating reaction mixtures by chemical reduction HALCON INTERNATIONAL, INC. (US) 1976-03-30 US claimed
US-3946115-A GRINDING, EXTRUSION RALSTON PURINA COMPANY (US) 1976-03-23 US claimed
US-3938997-A SUPER-ADDITIVE, THREE DEVELOPERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-02-17 US claimed
US-3934040-A FLOUR ADDITIVE OF CYSTEINE, ASCORBIC ACID, ENXYME, DOUGH CARAVAN PRODUCTS CO., INC. (US) 1976-01-20 US claimed
US-3932189-A Thermodevelopable photographic material containing high silver ion conducting substance FUJI PHOTO FILM CO., LTD. (JA) 1976-01-13 US claimed