Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588540 | 0.82 | CYP3A4 (0.48) | DYRK1AABL1ABCB1BCRSMN1; SMN2 | |
| SCHEMBL5805933 | 0.80 | ALDH1A1 (0.43) | MAPK1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL11099027 | 0.79 | ABL1 (0.52) | DYRK1AABL1ABCB1BCRMAPK1 | |
| SCHEMBL27720539 | 0.79 | ABL1 (0.47) | DYRK1AABL1ABCB1BCRMAPK1 | |
| SCHEMBL28824959 | 0.79 | ABL1 (0.52) | DYRK1AABL1ABCB1BCRMAPK1 | |
| SCHEMBL28095381 | 0.79 | ABL1 (0.47) | DYRK1AABL1ABCB1BCRMAPK1 | |
| SCHEMBL27588635 | 0.78 | TDP1 (0.50) | NPC1TP53RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL2021195 | 0.78 | — | — | |
| SCHEMBL6019039 | 0.78 | ABL1 (0.46) | DYRK1AABL1ABCB1BCRMAPK1 | |
| SCHEMBL8913087 | 0.75 | ABL1 (0.43) | DYRK1AABL1ABCB1BCRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087624-B2 | Substituted pyrazole compounds | TEIKOJU HORMONE MFG. CO., LTD. (JP) | 2006-08-08 | — | — | US | disclosed |
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |