Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.51 |
| ▸ | CALML3 | P27482 | 7/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SDHA | P31040 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182438 | 1.00 | MAOA (0.51) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3182433 | 1.00 | MAOA (0.51) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL10197431 | 0.94 | MAOA (0.53) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL18403019 | 0.91 | MAOA (0.51) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL13180769 | 0.91 | MAOA (0.54) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6023427 | 0.91 | CALML3 (0.55) | MAOACALML3MAOB | |
| SCHEMBL6023424 | 0.91 | CALML3 (0.55) | MAOACALML3MAOB | |
| SCHEMBL13528060 | 0.90 | CALML3 (0.48) | MAOACALML3MAOB | |
| SCHEMBL10197647 | 0.90 | MAOA (0.53) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6023800 | 0.87 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713785-A1 | HALOGENATED BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | Rib-X Pharmaceuticals, Inc. (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005061468-A1 | HALOGENATED BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2005-07-07 | — | — | WO | disclosed |