Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030120 | 1.00 | HCAR2 (0.41) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL6029814 | 1.00 | HCAR2 (0.41) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL9330586 | 0.87 | HCAR2 (0.41) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL5953984 | 0.83 | LTB4R (0.39) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL9330578 | 0.81 | HCAR2 (0.39) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL6029816 | 0.81 | HCAR2 (0.43) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL6030122 | 0.81 | HCAR2 (0.43) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL30782955 | 0.81 | HCAR2 (0.43) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL18978766 | 0.81 | HCAR2 (0.43) | HCAR2TAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL6030593 | 0.81 | HCAR2 (0.43) | HCAR2TAAR1ADRA2AADRA2CADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7057061-B2 | Chiral monophosphorus compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-06 | — | — | US | claimed |
| US-20030119664-A1 | Chiral monophosphorus compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2003-06-26 | — | — | US | claimed |
| US-7057061-B2 | Chiral monophosphorus compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-06 | — | — | US | disclosed |
| US-20030119664-A1 | Chiral monophosphorus compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2003-06-26 | — | — | US | disclosed |