Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | PER2 | O15055 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032231 | 0.81 | PRMT5 (0.43) | KDM4EHSD17B10MAPK1L3MBTL1RAB9A | |
| SCHEMBL6032136 | 0.80 | MAPT (0.43) | MAPK1L3MBTL1ABCB1ABCG2 | |
| SCHEMBL6031776 | 0.75 | PRMT5 (0.44) | KDM4EMAPK1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL6030382 | 0.72 | PRMT5 (0.45) | KDM4EALDH1A1HSD17B10MAPK1PER2 | |
| SCHEMBL6031507 | 0.72 | PRMT5 (0.53) | KDM4EALDH1A1MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL23469645 | 0.71 | PER2 (0.60) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL23469602 | 0.67 | PER2 (0.61) | ALDH1A1PER2SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL13751537 | 0.65 | KMT2A (0.44) | ALDH1A1SMN1; SMN2KMT2AMALT1RAB9A | |
| SCHEMBL5929386 | 0.64 | MALT1 (0.64) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL23469524 | 0.64 | PER2 (0.65) | KDM4EALDH1A1MAPK1PER2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678137-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005037791-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |