Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799566 | 0.92 | ELANE (0.72) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| SCHEMBL6282777 | 0.92 | KMT2A (0.68) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| SCHEMBL45119 | 0.92 | ELANE (0.72) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| Benzene SCHEMBL28089483 | 0.92 | ELANE (0.72) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| SCHEMBL31575762 | 0.90 | ELANE (0.70) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| SCHEMBL17028724 | 0.90 | ELANE (0.70) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| SCHEMBL376108 | 0.90 | ELANE (0.70) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| Ammonia Solution, Strong SCHEMBL22042017 | 0.90 | ELANE (0.70) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| Magnesium SCHEMBL31307540 | 0.90 | ELANE (0.70) | ELANESMN1; SMN2KMT2AESR1HIF1A | |
| Methane SCHEMBL6301524 | 0.90 | ELANE (0.70) | ELANESMN1; SMN2KMT2AESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101909451-A | Fungicidal mixtures II | BASF SE | 2010-12-08 | — | — | CN | claimed |
| CN-107207421-A | New trifluoromethyl propanamide derivative | 豪夫迈·罗氏有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-101909451-A | Fungicidal mixtures II | BASF SE | 2010-12-08 | — | — | CN | disclosed |
| EP-1652833-A1 | PROCESS FOR PRODUCING 4-HYDROXYDIPHENYL ETHER | Sumitomo Chemical Company, Limited (JP) | 2006-05-03 | — | — | EP | disclosed |
| CN-1147481-C | Pyrimidine-2,4,6-triones as inhibitors of matrix metalloproteinases | - | 2004-04-28 | — | — | CN | disclosed |
| CN-1339028-A | Pyrimidine-2,4,6-triones as inhibitors of matrix metalloproteinases | HOFFMANN LA ROCHE (CH) | 2002-03-06 | — | — | CN | disclosed |
| EP-0384230-A1 | Substituted phenoxyphenyl propionic acid derivatives | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-3985779-A | ANTIINFLAMMATORY AND ANALGESIC ACTIVITIES | EISAI CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |