Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094343 | 0.84 | MAPT (0.56) | TP53MAPTALDH1A1EPHX2NR1H4 | |
| SCHEMBL2468727 | 0.83 | TP53 (0.50) | TP53MAPTALDH1A1EPHX2NR1H4 | |
| SCHEMBL6031419 | 0.83 | PLK1 (0.41) | TP53MAPTLMNAPPARARHOC | |
| SCHEMBL5100823 | 0.79 | TP53 (0.50) | TP53MAPTALDH1A1EPHX2NR1H4 | |
| SCHEMBL2472568 | 0.78 | TP53 (0.49) | TP53MAPTALDH1A1EPHX2NR1H4 | |
| SCHEMBL14208442 | 0.77 | MAPT (0.57) | TP53MAPTALDH1A1LMNAPPARA | |
| SCHEMBL4964646 | 0.77 | MAPT (0.48) | TP53MAPTALDH1A1EPHX2NR1H4 | |
| SCHEMBL2473901 | 0.76 | TP53 (0.47) | TP53MAPTALDH1A1EPHX2NR1H4 | |
| SCHEMBL2473905 | 0.76 | TP53 (0.47) | TP53MAPTALDH1A1EPHX2NR1H4 | |
| SCHEMBL5100835 | 0.76 | MAPT (0.47) | TP53MAPTALDH1A1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656139-A1 | ARYL DICARBOXAMIDES | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-17 | — | — | EP | claimed |
| WO-2005011685-A1 | ARYL DICARBOXAMIDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | claimed |