Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 10/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 5/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466243 | 0.81 | PLK1 (0.53) | PLK1KAT8PPARGPPARAEPHX2 | |
| SCHEMBL2470089 | 0.78 | STAT3 (0.67) | PLK1KAT8LSS | |
| SCHEMBL2472789 | 0.78 | PLK1 (0.54) | PLK1KAT8PPARGPPARAEPHX2 | |
| SCHEMBL2470498 | 0.73 | STAT3 (0.57) | PLK1PPARGPPARAEPHX2LSS | |
| SCHEMBL2468230 | 0.70 | KAT8 (0.52) | PLK1KAT8PLK3TRPV1 | |
| SCHEMBL2468737 | 0.70 | PLK1 (0.50) | PLK1KAT8LSS | |
| SCHEMBL4321965 | 0.69 | LSS (0.57) | PLK1PPARGPPARAEPHX2LSS | |
| SCHEMBL2468215 | 0.68 | KAT8 (0.47) | PLK1KAT8TRPV1 | |
| SCHEMBL6022102 | 0.68 | LSS (0.47) | PLK1PPARGPPARAEPHX2LSS | |
| SCHEMBL6032331 | 0.68 | KAT8 (0.48) | PLK1KAT8PLK3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656139-A1 | ARYL DICARBOXAMIDES | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-17 | — | — | EP | claimed |
| WO-2005011685-A1 | ARYL DICARBOXAMIDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | claimed |