Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032299 | 1.00 | KMT2A (0.58) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL4275687 | 0.86 | KMT2A (0.64) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL27198359 | 0.86 | KMT2A (0.64) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL4275683 | 0.86 | KMT2A (0.64) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL5668373 | 0.86 | KMT2A (0.64) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL5663819 | 0.79 | KMT2A (0.58) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL5663817 | 0.79 | KMT2A (0.58) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL26222203 | 0.77 | KMT2A (0.56) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL91114 | 0.76 | ALDH1A1 (0.67) | KMT2AALDH1A1KDM4EGAAACHE | |
| SCHEMBL2164065 | 0.76 | ALDH1A1 (0.67) | KMT2AALDH1A1KDM4EGAAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656139-A1 | ARYL DICARBOXAMIDES | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005011685-A1 | ARYL DICARBOXAMIDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |