SCHEMBL6032446

SCHEMBL6032446

CC(=O)CCC(=O)S.CC(=O)CCC(=S)OC(=S)CCC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.37
SLC15A2 Q16348 1/20 0.37
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3490442 0.89 ALDH1A1 (0.56) ALDH1A1LMNASLC15A2TDP1
SCHEMBL3390367 0.81
SCHEMBL31126006 0.72
SCHEMBL11068035 0.68 ALDH1A1 (0.48) ALDH1A1LMNASLC15A2TDP1
SCHEMBL11428316 0.67 ALDH1A1 (0.46) ALDH1A1LMNASLC15A2
SCHEMBL28060459 0.66 ALDH1A1 (1.00) ALDH1A1LMNASLC15A2TDP1
SCHEMBL10001 0.66
SCHEMBL3071953 0.66
SCHEMBL9169879 0.66 PAOX (0.52) ALDH1A1LMNASLC15A2TDP1
SCHEMBL15135061 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620118-A2 REVERSIBLE PEGYLATED DRUGS YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) 2006-02-01 EP disclosed
WO-2004089280-A2 REVERSIBLE PEGYLATED DRUGS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2004-10-21 WO disclosed