Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066892 | 0.82 | CYP3A4 (0.41) | KDM4EKMT2AALDH1A1LMNA | |
| SCHEMBL6032746 | 0.81 | KDM4E (0.39) | SMN1; SMN2KDM4ECFTRSLC6A2SLC6A4 | |
| SCHEMBL9063416 | 0.79 | CYP2A6 (0.41) | SMN1; SMN2KDM4ECFTRSLC6A2SLC6A4 | |
| SCHEMBL28508279 | 0.77 | PTGS2 (0.41) | SMN1; SMN2KDM4EGAAALDH1A1LMNA | |
| SCHEMBL617213 | 0.70 | CYP3A4 (0.57) | SMN1; SMN2KDM4ECFTRSLC6A2SLC6A4 | |
| SCHEMBL25620250 | 0.70 | CYP3A4 (0.57) | SMN1; SMN2KDM4ECFTRSLC6A2SLC6A4 | |
| SCHEMBL13557811 | 0.69 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4ECFTRSLC6A2SLC6A4 | |
| SCHEMBL29143382 | 0.68 | — | — | |
| SCHEMBL12620100 | 0.68 | — | — | |
| SCHEMBL20530269 | 0.67 | CFTR (0.42) | SMN1; SMN2KDM4ECFTRSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598053-B1 | Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres | OREAL (FR) | 2006-12-20 | — | — | EP | claimed |