Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294072 | 0.90 | SPHK1 (0.42) | DNM1USP2SPHK1HTT | |
| SCHEMBL27695365 | 0.90 | SPHK1 (0.42) | DNM1USP2SPHK1HTT | |
| SCHEMBL27925080 | 0.90 | SPHK1 (0.42) | DNM1USP2SPHK1HTT | |
| SCHEMBL1465743 | 0.85 | DNM1 (0.47) | DNM1USP2SPHK1HTT | |
| SCHEMBL23038695 | 0.85 | DNM1 (0.47) | DNM1USP2SPHK1HTTLPAR1 | |
| SCHEMBL23038685 | 0.85 | DNM1 (0.47) | DNM1USP2SPHK1HTTLPAR1 | |
| SCHEMBL725926 | 0.85 | DNM1 (0.47) | DNM1USP2SPHK1HTT | |
| SCHEMBL21693799 | 0.85 | DNM1 (0.47) | DNM1USP2SPHK1HTT | |
| SCHEMBL10879025 | 0.85 | DNM1 (0.47) | DNM1USP2SPHK1HTT | |
| SCHEMBL11119607 | 0.85 | DNM1 (0.47) | DNM1USP2SPHK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666473-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |