Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | MC1R | Q01726 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033439 | 1.00 | KDM4E (0.51) | KDM4EGAAALDH1A1EPHX1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10603453 | 0.99 | KDM4E (0.50) | KDM4EGAAALDH1A1EPHX1HSD17B10 | |
| Dl-Phenylalanine SCHEMBL26965744 | 0.91 | MEN1 (0.50) | KDM4EGAAALDH1A1EPHX1HSD17B10 | |
| SCHEMBL26108204 | 0.87 | MEN1 (0.53) | KDM4EALDH1A1HSD17B10GSK3BNPY5R | |
| SCHEMBL14250016 | 0.83 | CYP2C9 (0.46) | NPY5RMAPTMEN1KMT2A | |
| SCHEMBL16213504 | 0.83 | KDM4E (0.48) | KDM4EGAAALDH1A1EPHX1HSD17B10 | |
| SCHEMBL16213507 | 0.83 | KDM4E (0.48) | KDM4EGAAALDH1A1EPHX1HSD17B10 | |
| SCHEMBL7860945 | 0.82 | MEN1 (0.51) | KDM4EALDH1A1HSD17B10GSK3BNPY5R | |
| SCHEMBL7860939 | 0.82 | MEN1 (0.51) | KDM4EALDH1A1HSD17B10GSK3BNPY5R | |
| SCHEMBL7918402 | 0.82 | MEN1 (0.51) | KDM4EALDH1A1HSD17B10GSK3BNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230407243-A1 | GENETIC PLATFORM TO INVESTIGATE THE FUNCTIONS OF BACTERIAL DRUG EFFLUX PUMPS | UNIVERSITY OF GUELPH (CA) | 2023-12-21 | — | — | US | disclosed |
| CN-101014363-A | Vaccine for periodontal disease | PFIZER PROD INC (US) | 2007-08-08 | — | — | CN | disclosed |
| US-7033781-B1 | Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating | DIVERSA CORPORATION (US) | 2006-04-25 | — | — | US | disclosed |
| US-20050124010-A1 | Whole cell engineering by mutagenizing a substantial portion of a starting genome combining mutations and optionally repeating | DIVERSA CORPORATION | 2005-06-09 | — | — | US | disclosed |
| US-20040077090-A1 | Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating | SHORT JAY M (US) | 2004-04-22 | — | — | US | disclosed |
| EP-1294869-A2 | WHOLE CELL ENGINEERING BY MUTAGENIZING A SUBSTANTIAL PORTION OF A STARTING GENOME, COMBINING MUTATIONS, AND OPTIONALLY REPEATING | DIVERSA CORPORATION (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096551-A2 | WHOLE CELL ENGINEERING BY MUTAGENIZING A SUBSTANTIAL PORTION OF A STARTING GENOME, COMBINING MUTATIONS, AND OPTIONALLY REPEATING | DIVERSA CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |