Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 10/20 | 0.47 |
| ▸ | NPY1R | P25929 | 6/20 | 0.47 |
| ▸ | NPY2R | P49146 | 4/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MC5R | P33032 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | MC1R | Q01726 | 1/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860939 | 1.00 | MEN1 (0.51) | MEN1KMT2AHSD17B10NPY4RNPY1R | |
| SCHEMBL7860945 | 1.00 | MEN1 (0.51) | MEN1KMT2AHSD17B10NPY4RNPY1R | |
| SCHEMBL26108204 | 0.92 | MEN1 (0.53) | MEN1KMT2AHSD17B10NPY4RNPY1R | |
| Dl-Phenylalanine SCHEMBL26965744 | 0.86 | MEN1 (0.50) | MEN1KMT2AHSD17B10NPY4RNPY1R | |
| SCHEMBL15921797 | 0.85 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL290268 | 0.84 | NPC1 (0.50) | MEN1KMT2AHSD17B10KDM4EGSK3B | |
| SCHEMBL290267 | 0.84 | NPC1 (0.50) | MEN1KMT2AHSD17B10KDM4EGSK3B | |
| SCHEMBL28896050 | 0.84 | MC4R (0.60) | MEN1KMT2AHSD17B10KDM4EGSK3B | |
| Pabetan SCHEMBL4546522 | 0.84 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| Pabetan SCHEMBL21571465 | 0.84 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018132920-A1 | PEPTIDE INHIBITOR OF TRANSMEMBRANE PORE FORMATION AND EFFLUXPUMP FUNCTION IN A SMALL MULTIDRUG RESISTANCE PROTEIN FROM PSEUDOMONAS AERUGINOSA | THE HOSPITAL FOR SICK CHILDREN (CA) | 2018-07-26 | — | — | WO | disclosed |
| EP-1077718-A1 | ENHANCEMENT OF OXAZOLIDINONE ANTIBACTERIAL AGENTS ACTIVITY BY ARGININE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059616-A1 | ENHANCEMENT OF OXAZOLIDINONE ANTIBACTERIAL AGENTS ACTIVITY BY USING ARGININE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |