Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033649 | 0.95 | TRPV1 (0.54) | TRPV1MAPK3 | |
| SCHEMBL6033545 | 0.92 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL5809097 | 0.81 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL5801087 | 0.80 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL5808575 | 0.78 | TRPV1 (0.47) | TRPV1MAPK3 | |
| SCHEMBL6033610 | 0.77 | TRPV1 (0.60) | TRPV1MAPK3 | |
| SCHEMBL6033564 | 0.77 | TRPV1 (0.48) | TRPV1MAPK3 | |
| SCHEMBL5799338 | 0.76 | TRPV1 (0.46) | TRPV1MAPK3 | |
| SCHEMBL27700950 | 0.75 | TRPV1 (0.39) | TRPV1MAPK3 | |
| SCHEMBL5814291 | 0.74 | TRPV1 (0.50) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685124-A1 | SUBSTITUTED NITROGEN-CONTAINING SIX-MEMBERED AMINO-HETEROCYCLES AS VANILLOID-1 RECEPTOR ANTAGONISTS FOR TREATING PAIN | MERCK SHARP & DOHME LTD. (GB) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047279-A1 | SUBSTITUTED NITROGEN-CONTAINING SIX-MEMBERED AMINO-HETEROCYCLES AS VANILLOID-1 RECEPTOR ANTAGONISTS FOR TREATING PAIN | MERCK SHARP & DOHME LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |