Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 7/20 | 0.61 |
| ▸ | KDR | P35968 | 3/20 | 0.58 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1265193 | 0.79 | TEK (0.85) | TEKKDR | |
| SCHEMBL1264767 | 0.78 | TEK (0.72) | TEKKDR | |
| SCHEMBL2299531 | 0.78 | TEK (0.74) | TEKKDR | |
| SCHEMBL1265742 | 0.76 | TEK (0.79) | TEKKDR | |
| SCHEMBL1265216 | 0.76 | TEK (1.00) | TEKKDR | |
| SCHEMBL1265726 | 0.75 | TEK (0.77) | TEKKDR | |
| SCHEMBL1265264 | 0.74 | TEK (1.00) | TEKKDR | |
| SCHEMBL1265600 | 0.74 | TEK (1.00) | TEKKDR | |
| SCHEMBL1264291 | 0.74 | TEK (0.82) | TEKKDR | |
| SCHEMBL1265046 | 0.73 | TEK (0.85) | TEKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060009453-A1 | Protein kinase modulators and method of use | AMGEN INC. | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009453-A1 | Protein kinase modulators and method of use | PHKG1, PRKCH, BMP2K | TEK 215/4885KDR 58/4885IRAK4 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.