Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943334 | 0.85 | MCL1 (0.71) | MCL1MYCFTOLDHAALDH1A1 | |
| SCHEMBL107259 | 0.82 | CSNK2A1 (0.59) | MCL1NFE2L2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL30679777 | 0.82 | CSNK2A1 (0.59) | MCL1NFE2L2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL29064695 | 0.81 | MYC (0.56) | MCL1HDAC7NFE2L2MYCKDM4E | |
| SCHEMBL3229733 | 0.81 | HDAC7 (0.70) | HDAC7MYCLDHAKDM4EALDH1A1 | |
| SCHEMBL6915656 | 0.80 | CSNK2A1 (0.57) | MCL1NFE2L2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL6915500 | 0.80 | CSNK2A1 (0.57) | MCL1NFE2L2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL6915319 | 0.80 | CSNK2A1 (0.57) | MCL1NFE2L2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL6908325 | 0.80 | CSNK2A1 (0.57) | MCL1NFE2L2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL6915580 | 0.80 | CSNK2A1 (0.57) | MCL1NFE2L2KDM4EALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716867-A1 | PREVENTIVES FOR MIGRAINE | Astellas Pharma Inc. (JP) | 2006-11-02 | — | — | EP | disclosed |