Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15402968 | 0.76 | — | — | |
| SCHEMBL5191388 | 0.75 | TET2 (0.47) | TSHRKDM4ETDP1 | |
| SCHEMBL25858196 | 0.75 | TSHR (0.37) | TSHRKDM4ETDP1USP2LMNA | |
| SCHEMBL25982471 | 0.75 | KDM4E (0.31) | TSHRKDM4ETDP1 | |
| SCHEMBL25858208 | 0.72 | — | — | |
| SCHEMBL28752324 | 0.70 | KDM4E (0.30) | TSHRKDM4ETDP1 | |
| SCHEMBL186999 | 0.69 | KDM4E (0.31) | TSHRKDM4ETDP1 | |
| SCHEMBL157749 | 0.69 | KDM4E (0.31) | TSHRKDM4ETDP1 | |
| SCHEMBL31327517 | 0.69 | LMNA (0.35) | TSHRKDM4EMAPTS1PR4ALDH1A1 | |
| SCHEMBL8615910 | 0.69 | TSHR (0.38) | TSHRKDM4ETDP1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281644-A1 | Method to synthesize fluorinated ZDDP | PLATINUM RESEARCH ORGANIZATION (US) | 2006-12-14 | — | — | US | disclosed |