SCHEMBL6034236

SCHEMBL6034236

CN1c2ccc(C(=O)CCCCNCCc3ccccc3Cl)cc2N(C)S1(O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.38
CHRM2 P08172 1/20 0.37
SLC2A1 P11166 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PLAAT3 P53816 1/20 0.36
PLAAT5 Q96KN8 1/20 0.36
PLAAT2 Q9NWW9 1/20 0.36
PLAAT4 Q9UL19 1/20 0.36
MAPT P10636 1/20 0.36
TAAR1 Q96RJ0 2/20 0.35
MCHR1 Q99705 1/20 0.35
TRPV1 Q8NER1 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
NAMPT P43490 1/20 0.34
HTR7 P34969 1/20 0.34
CXCR3 P49682 1/20 0.34
TP53 P04637 1/20 0.33
BACE1 P56817 1/20 0.33
CNR1 P21554 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4895011 0.99 HIF1A (0.38) HIF1ACHRM2SLC2A1MEN1KMT2A
SCHEMBL6034225 0.92 HIF1A (0.38) HIF1ACHRM2SLC2A1MEN1KMT2A
Hydrochloric Acid SCHEMBL4895005 0.91 HIF1A (0.38) HIF1ACHRM2SLC2A1MEN1KMT2A
Hydrochloric Acid SCHEMBL4887555 0.86 MCHR1 (0.37) HIF1ACHRM2SLC2A1MEN1KMT2A
SCHEMBL27592961 0.86 HIF1A (0.40) HIF1ACHRM2SLC2A1MEN1KMT2A
SCHEMBL6036076 0.83 TAAR1 (0.37) KMT2ATAAR1MCHR1TP53CNR1
Hydrochloric Acid SCHEMBL4880703 0.82 TAAR1 (0.36) MEN1KMT2AMAPTTAAR1MCHR1
SCHEMBL4887165 0.82 TAAR1 (0.33) HIF1APLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL13987739 0.81 MCHR1 (0.37) HIF1ACHRM2SLC2A1MEN1KMT2A
SCHEMBL13988054 0.81 MAPT (0.39) CHRM2SLC2A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060063769-A1 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063769-A1 Preventives/remedies for urinary disturbance ACHE, BPHL, CHRM1 HIF1A 2216/4885CHRM2 9/4885SLC2A1 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.