SCHEMBL6034302

SCHEMBL6034302

CN(CCCCC(=O)c1cc2c3c(c1)CC(=O)N3CCC2)CCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.58
NPC1 O15118 1/20 0.55
TTR P02766 1/20 0.55
ALDH1A1 P00352 1/20 0.50
RAD52 P43351 1/20 0.46
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13987318 0.99 ACHE (0.57) ACHENPC1TTRALDH1A1RAD52
Hydrochloric Acid SCHEMBL4854931 0.99 ACHE (0.57) ACHENPC1TTRALDH1A1RAD52
SCHEMBL13987327 0.95 ACHE (0.58) ACHENPC1TTRALDH1A1
SCHEMBL13987340 0.94 ACHE (0.58) ACHENPC1TTRALDH1A1
Hydrochloric Acid SCHEMBL4915485 0.94 ACHE (0.58) ACHENPC1TTRALDH1A1
SCHEMBL13987313 0.90 NPC1 (0.50) ACHENPC1TTRRAD52
SCHEMBL6035462 0.89 ACHE (0.55) ACHENPC1TTRRAD52LMNA
SCHEMBL6035333 0.89 ACHE (0.57) ACHEALDH1A1THRATHRB
SCHEMBL13987319 0.89 NPC1 (0.49) ACHENPC1TTRRAD52
SCHEMBL6035083 0.89 ACHE (0.54) ACHENPC1TTRRAD52LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7462628-B2 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-09 US disclosed
US-7462628-B2 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-09 US disclosed
US-20060063769-A1 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063769-A1 Preventives/remedies for urinary disturbance ACHE, BPHL, CHRM1 ACHE 1/4885NPC1 1160/4885TTR 3069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.