Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695157 | 0.96 | CYP1A2 (0.47) | PRSS1PRSS2PRSS3CYP1A2CYP2C19 | |
| SCHEMBL6035582 | 0.92 | PRSS1 (0.45) | PRSS1PRSS2PRSS3CYP1A2CYP2C19 | |
| SCHEMBL6036105 | 0.92 | TSHR (0.49) | PRSS1PRSS2PRSS3SMN1; SMN2TSHR | |
| SCHEMBL6036084 | 0.90 | KDM4E (0.53) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL6034422 | 0.90 | SLC6A3 (0.47) | PRSS1PRSS2PRSS3CYP1A2CYP2C19 | |
| SCHEMBL5695176 | 0.88 | TSHR (0.46) | CYP1A2CYP2C19SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL5695129 | 0.88 | TSHR (0.50) | PRSS1PRSS2PRSS3SMN1; SMN2TSHR | |
| SCHEMBL5695160 | 0.85 | PPARG (0.48) | CYP1A2CYP2C19SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL5695165 | 0.85 | KDM4E (0.55) | TSHRCYP3A4TP53MAPK1ALDH1A1 | |
| SCHEMBL6035268 | 0.84 | TSHR (0.51) | PRSS1PRSS2PRSS3TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984741-B2 | 5-Nitrobenzofurans | BAYER AKTIENGESELLSCHAFT (DE) | 2006-01-10 | — | — | US | disclosed |
| US-20050288519-A1 | 5-Nitrobenzofurans | MAGERLEIN WOLFGANG | 2005-12-29 | — | — | US | disclosed |
| CN-1485323-A | 5-nitrobenzofurans | — | 2004-03-31 | — | — | CN | disclosed |
| US-20040034220-A1 | 5-Nitrobenzofurans | LANXESS DEUTSCHLAND GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288519-A1 | 5-Nitrobenzofurans | NOX5, NQO1, NDUFS5 | PRSS1 3855/4885PRSS2 3096/4885PRSS3 3032/4885 |
| US-20040034220-A1 | 5-Nitrobenzofurans | NOX5, NQO1, NDUFS5 | PRSS1 3855/4885PRSS2 3096/4885PRSS3 3032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.