Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034481 | 0.88 | FFAR1 (0.43) | PPARGPPARDPPARAFFAR1GCGR | |
| SCHEMBL6036006 | 0.88 | CNR1 (0.42) | PPARGPPARDPPARAFFAR1GCGR | |
| SCHEMBL6035581 | 0.85 | PPARG (0.43) | PPARGPPARDPPARAFFAR1GCGR | |
| SCHEMBL6035914 | 0.85 | PPARG (0.43) | PPARGPPARDPPARAFFAR1GCGR | |
| SCHEMBL6036184 | 0.84 | FFAR4 (0.45) | PPARGPPARDPPARAFFAR1GCGR | |
| SCHEMBL6035886 | 0.84 | FFAR4 (0.45) | PPARGPPARDPPARAFFAR1GCGR | |
| SCHEMBL6034968 | 0.84 | HCRTR1 (0.38) | PPARGPPARDFFAR1GCGRFFAR2 | |
| SCHEMBL6036338 | 0.84 | AKR1C3 (0.40) | PPARGPPARDPPARAGCGR | |
| SCHEMBL6035517 | 0.84 | FFAR4 (0.38) | PPARGPPARDPPARAFFAR1GCGR | |
| SCHEMBL6035224 | 0.84 | SMN1; SMN2 (0.39) | PPARGPPARDPPARAGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | PPARG 1037/4885PPARD 2488/4885PPARA 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.