SCHEMBL603533

SCHEMBL603533

C=C[Si](C)(C)COC(=O)C(=C)C#N

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
TSHR P16473 1/20 0.55
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL602435 0.82 ALDH1A1 (0.62) ALDH1A1TSHRCYP2C9
SCHEMBL2958964 0.78 TSHR (0.44) ALDH1A1TSHR
SCHEMBL9620528 0.77 ALDH1A1 (0.61) ALDH1A1TSHRCYP2C9
SCHEMBL9616984 0.74 MCL1 (0.31)
Butadiene SCHEMBL10811584 0.73 ALDH1A1 (0.85) ALDH1A1TSHRCYP2C9
SCHEMBL30940 0.72 TSHR (0.59) ALDH1A1TSHRCYP2C9
Acrylonitrile SCHEMBL10893622 0.71 ALDH1A1 (0.81) ALDH1A1TSHRCYP2C9
SCHEMBL604549 0.71 TSHR (0.58) ALDH1A1TSHR
SCHEMBL29445 0.71
SCHEMBL22770084 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4331796-A1 ACTINIC RADIATION CURABLE CYANOACRYLATE COMPOSITIONS FOR CERAMICS AND INVESTMENT CASTING ARKEMA FRANCE (FR) 2024-03-06 EP disclosed
US-20220213245-A1 LIGHT-CURABLE COMPOSITIONS USEFUL FOR FORMING COMPOSITE MATERIALS ARKEMA FRANCE (FR) 2022-07-07 US disclosed
WO-2021039799-A1 CURABLE COMPOSITION 株式会社日本触媒 2021-03-04 WO disclosed
US-10276284-B2 Methods and apparatus for preparing power transmission cables TYCO ELECTRONICS RAYCHEM GMBH (DE) 2019-04-30 US disclosed
US-10240047-B2 Cyanoacrylate composition and coating method using the cyanoacrylate composition THREEBOND CO., LTD. (JP) 2019-03-26 US disclosed
US-20180174713-A1 METHODS AND APPARATUS FOR PREPARING POWER TRANSMISSION CABLES TE CONNECTIVITY ENERGY GMBH (DE) 2018-06-21 US disclosed
US-9950042-B2 Extended length botulinum toxin formulation for human or mammalian use REVANCE THERAPEUTICS, INC. (US) 2018-04-24 US disclosed
US-9934889-B2 Methods and apparatus for preparing power transmission cables TYCO ELECTRONICS RAYCHEM GMBH (DE) 2018-04-03 US disclosed
US-20170260398-A1 CYANOACRYLATE COMPOSITION AND COATING METHOD USING THE CYANOACRYLATE COMPOSITION THREEBOND CO., LTD. (JP) 2017-09-14 US disclosed
US-9533070-B2 Therapeutic agent for pulmonary emphysema TERUMO KABUSHIKI KAISHA (JP) 2017-01-03 US disclosed
US-20040087710-A1 Cyanoadhesive composition for toy articles MATTEL, INC. 2004-05-06 US disclosed
US-6660327-B2 Imparting shear, peeling and wear resistance as well as tensile and impact strength; curing styrenic copolymer, alpha cyanoacrylate and volatile solvent on thermoplastic elastomeric substrate MATTEL, INC. 2003-12-09 US disclosed
US-20030125443-A1 Cyanoadhesive composition for toy articles MATTEL, INC. 2003-07-03 US disclosed
EP-1124159-B1 Photocurable composition THREE BOND CO LTD (JP) 2003-03-12 EP disclosed
US-6503959-B1 Composition also including cleavage photoinitiator THREE BOND CO., LTD. (JP) 2003-01-07 US disclosed
EP-0769721-B1 Photocurable composition THREE BOND CO LTD (JP) 2002-01-02 EP disclosed
EP-1124159-A1 Photocurable composition THREE BOND CO., LTD. (JP) 2001-08-16 EP disclosed
US-5994464-A ELASTOMER MISCIBLE OR COMPATIBLE WITH THE CYANOACRYLATE MONOMER AND CORE-SHELL POLYMER HAVING A RUBBERY CORE AND A SHELL OF A GLASSY POLYMER, THE CORE-SHELL POLYMER BEING COMPATIBLE BUT NOT MISCIBLE WITH THE CYANOACRYLATE MONOMER. THREE BOND., LTD. (JP) 1999-11-30 US disclosed
US-5824180-A CYANOACRYLATE ADHESIVE, METALLOCENE CURING ACCELERATOR THREE BOND CO., LTD. (JP) 1998-10-20 US disclosed
EP-0769721-A1 Photocurable composition THREE BOND CO., LTD. (JP) 1997-04-23 EP disclosed