Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035613 | 0.95 | TP53 (0.41) | FFAR4FFAR1FFAR2PPARAPPARD | |
| SCHEMBL6035545 | 0.94 | FFAR4 (0.39) | FFAR4FFAR1FFAR2PPARAPPARD | |
| SCHEMBL6035391 | 0.94 | FFAR4 (0.39) | FFAR4FFAR1FFAR2PPARAPPARD | |
| SCHEMBL6036172 | 0.92 | FFAR4 (0.38) | FFAR4FFAR1FFAR2PPARAPPARD | |
| SCHEMBL6034650 | 0.91 | FFAR4 (0.43) | FFAR4FFAR1FFAR2PPARAPPARD | |
| SCHEMBL6035174 | 0.91 | FFAR4 (0.44) | FFAR4FFAR1FFAR2PPARG | |
| SCHEMBL6034463 | 0.90 | PPARD (0.43) | PPARAPPARDKMT2ANR1H2NR1H3 | |
| SCHEMBL6035151 | 0.90 | FFAR4 (0.49) | FFAR4FFAR1FFAR2PPARAPPARD | |
| SCHEMBL6035275 | 0.90 | PPARA (0.47) | FFAR4FFAR1FFAR2PPARAPPARD | |
| SCHEMBL6035718 | 0.89 | FFAR4 (0.45) | FFAR4FFAR1FFAR2PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | FFAR4 195/4885FFAR1 376/4885FFAR2 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.