SCHEMBL6035448

SCHEMBL6035448

Cc1cccc(C(O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.52
ACP3 P15309 1/20 0.50
EPHX1 P07099 1/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
AOC3 Q16853 1/20 0.42
TAAR1 Q96RJ0 1/20 0.40
PARP1 P09874 1/20 0.40
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
OPRL1 P41146 1/20 0.39
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
HSD17B2 P37059 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822105 0.85 ACHE (0.52) ACHEACP3EPHX1TP53TDP1
SCHEMBL11606507 0.85 ACHE (0.52) ACHEACP3EPHX1TP53TDP1
SCHEMBL14087826 0.83 ACHE (0.50) ACHEACP3EPHX1TP53TDP1
SCHEMBL3071260 0.83 ACHE (0.50) ACHEACP3EPHX1TP53TDP1
SCHEMBL343187 0.83 ACHE (0.50) ACHEACP3EPHX1TP53TDP1
SCHEMBL429838 0.83 ACHE (0.50) ACHEACP3EPHX1TP53TDP1
SCHEMBL6055386 0.81 ACHE (0.48) ACHEACP3EPHX1TP53TDP1
SCHEMBL27985896 0.81 ACHE (0.48) ACHEACP3EPHX1TP53TDP1
SCHEMBL28388603 0.81 ACHE (0.48) ACHEACP3EPHX1TP53TDP1
SCHEMBL27955214 0.81 ACHE (0.48) ACHEACP3EPHX1TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102701912-A Synthetic method of 2,5-dimethyl-1,3-dihydro-1H-indene-2-base methanol essence JINGJIANG TAIDA PERFUME CHEMICAL CO LTD 2012-10-03 CN claimed
CN-118995087-A Adhesive film and dicing film-die bonding film 株式会社力森诺科 2024-11-22 CN disclosed
CN-110945634-B Heat-dissipating die bonding film and dicing die bonding film 株式会社力森诺科 2023-08-29 CN disclosed
WO-2023140165-A1 PRODUCTION METHOD FOR POLYALCOHOL 三菱ケミカル株式会社 2023-07-27 WO disclosed
CN-114730706-A Method for manufacturing semiconductor device, dicing die-bonding integrated film, and method for manufacturing the same 昭和电工材料株式会社 2022-07-08 CN disclosed
CN-114641848-A Dicing die-bonding integrated film, method for manufacturing the same, and method for manufacturing semiconductor device 昭和电工材料株式会社 2022-06-17 CN disclosed
CN-114641849-A Dicing die-bonding integrated film, method for manufacturing the same, and method for manufacturing semiconductor device 昭和电工材料株式会社 2022-06-17 CN disclosed
CN-113348533-B Method for evaluating pickup property, die-cut/die-bond integrated film, method for evaluating the same, method for sorting the same, and method for manufacturing semiconductor device 昭和电工材料株式会社 2022-06-03 CN disclosed
US-20140259329-A1 DECORATIVE FOAM AND METHOD NIKE, INC. 2014-09-18 US disclosed
CN-102701912-A Synthetic method of 2,5-dimethyl-1,3-dihydro-1H-indene-2-base methanol essence JINGJIANG TAIDA PERFUME CHEMICAL CO LTD 2012-10-03 CN disclosed
US-20090246137-A1 PYRIDYL DERIVATIVES AS CFTR MODULATORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2009-10-01 US disclosed
US-20080269245-A1 Dioxanes and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2008-10-30 US disclosed
CN-101239932-A Preparation of 3,5-di(2-cyano-isopropyl)-toluene UNIV EAST CHINA NORMAL (CN) 2008-08-13 CN disclosed
EP-0238753-B1 N-SUBSTITUTED CONDENSED POLYMETHYLENE IMINE DERIVATIVES BEECHAM GROUP PLC (GB) 1992-01-15 EP disclosed
US-4959374-A HYPOTENSIVE AGENTS, ANTICOAGULANTS, GLAUCOMA, HYPERGLYCEMIC AGENTS, ANTIDEPRESSANTS BEECHAM GROUP P.L.C. (GB) 1990-09-25 US disclosed
US-4863946-A HYPOGLYCEMIC AND HYPOTENSIVE AGENTS BEECHAM GROUP PLC (GB) 1989-09-05 US disclosed
EP-0311387-A2 Aromatic amine resins, their production process and thermosetting resin compositions making use of the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-12 EP disclosed
EP-0238753-A1 N-substituted condensed polymethylene imine derivatives BEECHAM GROUP PLC (GB) 1987-09-30 EP disclosed
EP-0187008-A2 Composition and method for producing a heat of steel Bergman, Donald George (US) 1986-07-09 EP disclosed
US-4130719-A POLY(METHYLENEBENZOATES STANDARD OIL COMPANY (INDIANA) (US) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090246137-A1 PYRIDYL DERIVATIVES AS CFTR MODULATORS CFTR, ABCC4, ABCB1 ACHE 4495/4885ACP3 4559/4885EPHX1 1901/4885
US-20080269245-A1 Dioxanes and uses thereof UTS2R, MAN2B2, AMDHD2 ACHE 4723/4885ACP3 1416/4885EPHX1 1452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.