Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6034974 | 0.99 | CCR5 (0.66) | CCR5CYP3A4CYP2C9 | |
| SCHEMBL5350799 | 0.82 | CCR5 (0.82) | CCR5CYP3A4CYP2C9 | |
| SCHEMBL5357388 | 0.82 | CCR5 (0.79) | CCR5CYP3A4CYP2C9 | |
| SCHEMBL5347191 | 0.81 | CCR5 (0.80) | CCR5CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL5356248 | 0.81 | CCR5 (0.79) | CCR5CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL5347701 | 0.81 | CCR5 (0.82) | CCR5CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL5344327 | 0.81 | CCR5 (0.80) | CCR5CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL6190407 | 0.81 | CCR5 (0.80) | CCR5CYP3A4CYP2C9 | |
| SCHEMBL6033779 | 0.80 | CCR5 (0.57) | CCR5CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL6186920 | 0.80 | CCR5 (0.79) | CCR5CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060019977-A1 | Spiroheterocyclic derivative compounds and drugs comprising the compound as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-26 | — | — | US | claimed |
| EP-1553098-A1 | SPIROHETEROCYCLIC DERIVATIVE COMPOUNDS AND DRUGS COMPRISING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-07-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019977-A1 | Spiroheterocyclic derivative compounds and drugs comprising the compound as the active ingredient | CCR1, ACKR3, CCR10 | CCR5 7/4885CYP3A4 1409/4885CYP2C9 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.