Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035566 | 1.00 | HPGD (0.41) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6035593 | 0.86 | HPGD (0.40) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6035587 | 0.86 | HPGD (0.40) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6034476 | 0.85 | HDAC4 (0.40) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6034471 | 0.85 | HDAC4 (0.40) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6035842 | 0.84 | SMN1; SMN2 (0.40) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6034585 | 0.84 | SMN1; SMN2 (0.40) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6035837 | 0.84 | SMN1; SMN2 (0.40) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6034584 | 0.84 | SMN1; SMN2 (0.40) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL716206 | 0.83 | KDM4E (0.44) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | HPGD 3297/4885CYP1A2 95/4885CYP2C9 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.