Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | GCG | P01275 | 3/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632906 | 0.92 | GCGR (0.34) | GCGRGCGPANK3SMN1; SMN2HDAC4 | |
| SCHEMBL6034614 | 0.87 | GCGR (0.39) | GCGRGCGSMN1; SMN2HDAC4HPGD | |
| SCHEMBL6253122 | 0.85 | PANK3 (0.35) | GCGRPANK3SMN1; SMN2HDAC4HRH3 | |
| SCHEMBL6036397 | 0.84 | GCGR (0.36) | GCGRGCGSMN1; SMN2HDAC4HRH3 | |
| SCHEMBL6036015 | 0.83 | GCGR (0.35) | GCGRGCGPANK3SMN1; SMN2HDAC4 | |
| SCHEMBL6034481 | 0.82 | FFAR1 (0.43) | GCGRGCGL3MBTL1LMNAPPARG | |
| SCHEMBL6034968 | 0.82 | HCRTR1 (0.38) | GCGRSMN1; SMN2HCRTR1HCRTR2KDM4E | |
| SCHEMBL6035903 | 0.82 | SMN1; SMN2 (0.41) | GCGRSMN1; SMN2HDAC4HPGDHCRTR1 | |
| SCHEMBL6035517 | 0.82 | FFAR4 (0.38) | GCGRSMN1; SMN2KDM4EPPARG | |
| SCHEMBL6036403 | 0.81 | GCGR (0.36) | GCGRGCGSMN1; SMN2HDAC4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | GCGR 93/4885GCG 284/4885PANK3 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.