Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 14/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036423 | 0.96 | PPARD (0.40) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6035524 | 0.94 | PPARD (0.43) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6035430 | 0.94 | PPARD (0.41) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6035112 | 0.91 | PPARD (0.42) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6034876 | 0.91 | NR1H2 (0.40) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6035258 | 0.88 | PPARD (0.40) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6035712 | 0.87 | PPARG (0.44) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6036038 | 0.87 | FFAR4 (0.45) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6036342 | 0.87 | FFAR4 (0.45) | PPARDNR1H2NR1H3PPARAPPARG | |
| SCHEMBL6035233 | 0.86 | PPARD (0.43) | PPARDNR1H2NR1H3PPARATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | PPARD 2488/4885NR1H2 12/4885NR1H3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.