Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7162067 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| Sulfuric Acid SCHEMBL27786114 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| Sulfuric Acid SCHEMBL30366425 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| SCHEMBL11708122 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| Sulfuric Acid SCHEMBL28066175 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| Sulfuric Acid SCHEMBL28066176 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| Sulfuric Acid SCHEMBL10787415 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| Sulfuric Acid SCHEMBL27690122 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| 3-Aminophenol SCHEMBL27876217 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| Sulfuric Acid Dimethyl Ester SCHEMBL11884144 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRHSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060275329-A1 | Flavin protein of trypanosoma cruzi, method of screening vermicide with the use of the same and diagnostic | OSAKA BIOSCIENCE INSTITUTE (JP) | 2006-12-07 | — | — | US | disclosed |
| US-5320725-A | Electrode and method for the detection of hydrogen peroxide | E. HELLER & COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| WO-1993023748-A1 | ELECTRODE AND METHOD FOR THE DETECTION OF HYDROGEN PEROXIDE | E. HELLER & COMPANY (US) | 1993-11-25 | — | — | WO | disclosed |