⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774128 | 0.72 | — | — | |
| SCHEMBL6178684 | 0.71 | — | — | |
| SCHEMBL4368207 | 0.67 | — | — | |
| SCHEMBL2781558 | 0.65 | — | — | |
| SCHEMBL1400031 | 0.65 | EPHX1 (0.39) | — | |
| Methylamine SCHEMBL28124183 | 0.59 | — | — | |
| SCHEMBL438915 | 0.58 | — | — | |
| SCHEMBL26452946 | 0.58 | GBA1 (0.44) | — | |
| SCHEMBL12018640 | 0.58 | — | — | |
| SCHEMBL788564 | 0.58 | GBA1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680429-A1 | THIENO-PYRIDINONE DERIVATIVES AS KINASE INHIBITORS | Celltech R & D Limited (GB) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005042540-A1 | THIENO-PYRIDINONE DERIVATIVES AS KINASE INHIBITORS | CELLTECH R & D LIMITED (GB) | 2005-05-12 | — | — | WO | disclosed |