SCHEMBL6036744

SCHEMBL6036744

C=C(C)C(=O)OCC(O)CC(=C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
TET2 Q6N021 4/20 0.42
TET3 O43151 1/20 0.42
TET1 Q8NFU7 1/20 0.42
THRB P10828 1/20 0.38
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
GRM1 Q13255 1/20 0.37
GRM2 Q14416 1/20 0.37
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13114671 0.85 TSHR (0.57) TSHRTHRBALDH1A1
SCHEMBL11598309 0.85 TSHR (0.49) TSHRTET2TET3TET1THRB
SCHEMBL3095132 0.85 TET2 (0.39) TSHRTET2TET3TET1GRIK1
SCHEMBL11598301 0.85 TSHR (0.49) TSHRTET2TET3TET1THRB
SCHEMBL28343113 0.84 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL872099 0.83 TSHR (0.50) TSHRTET2TET3TET1THRB
SCHEMBL94906 0.82 TSHR (0.68) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL19998240 0.81 TSHR (0.65) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL25415594 0.80 TSHR (0.55) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL5435140 0.80 TSHR (0.55) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1209492-B1 Formation of materials such as waveguides with a refractive index step NAT UNIV IRELAND CORK (IE) 2004-02-04 EP claimed
WO-2015082244-A1 STABILIZER FOR THIOL-ENE COMPOSITIONS ALLNEX BELGIUM , S.A. (BE) 2015-06-11 WO disclosed
EP-2518014-A1 CARBON MICROPARTICLE AND PROCESS FOR PRODUCTION THEREOF Toray Industries, Inc. (JP) 2012-10-31 EP disclosed
EP-1633805-A1 METHOD FOR PRODUCING SCRATCH-RESISTANT COATING SYSTEMS DEVOID OF CONDENSATION Bayer MaterialScience AG (DE) 2006-03-15 EP disclosed
EP-1565768-A1 LAMINATED SYSTEM, COATING COMPOSITION AND METHOD FOR THE PRODUCTION THEREOF Bayer MaterialScience AG (DE) 2005-08-24 EP disclosed
EP-1549701-A1 METHOD FOR PRODUCING A SCRATCH-RESISTANT LAYER SYSTEM Bayer MaterialScience AG (DE) 2005-07-06 EP disclosed
EP-1549700-A1 LAYER SYSTEM AND METHOD FOR PRODUCING THE SAME Bayer MaterialScience AG (DE) 2005-07-06 EP disclosed
WO-2004108801-A1 METHOD FOR PRODUCING SCRATCH-RESISTANT COATING SYSTEMS DEVOID OF CONDENSATION BAYER MATERIALSCIENCE AG (DE) 2004-12-16 WO disclosed
WO-2004044627-A1 LAMINATED SYSTEM, COATING COMPOSITION AND METHOD FOR THE PRODUCTION THEREOF BAYER MATERIALSCIENCE AG (DE) 2004-05-27 WO disclosed
WO-2004031272-A1 METHOD FOR PRODUCING A SCRATCH-RESISTANT LAYER SYSTEM BAYER MATERIALSCIENCE AG (DE) 2004-04-15 WO disclosed
US-5188900-A Substrates having an abrasion-resistant coating formed thereon DOW CORNING CORPORATION (US) 1993-02-23 US disclosed
US-5126394-A Silane-free DOW CORNING CORPORATION (US) 1992-06-30 US disclosed
EP-0439294-A1 Alkoxy-functional silane compositions for unprimed adhesion to polycarbonate DOW CORNING CORPORATION (US) 1991-07-31 EP disclosed
EP-0439293-A1 Alkoxy-functional silane compositions for unprimed adhesion to polycarbonate DOW CORNING CORPORATION (US) 1991-07-31 EP disclosed
EP-0424006-A2 Silane free radiation curable abrasion resistant coatings DOW CORNING CORPORATION (US) 1991-04-24 EP disclosed
EP-0307097-A2 Water-insolubilized cytokines Takeda Chemical Industries, Ltd. (JP) 1989-03-15 EP disclosed
EP-0055726-A4 ABRASION RESISTANT ULTRAVIOLET LIGHT CURABLE HARD COATING COMPOSITIONS. GEN ELECTRIC (US) 1982-11-25 EP disclosed
US-4348462-A Abrasion resistant ultraviolet light curable hard coating compositions GENERAL ELECTRIC COMPANY (US) 1982-09-07 US disclosed
EP-0055726-A1 ABRASION RESISTANT ULTRAVIOLET LIGHT CURABLE HARD COATING COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1982-07-14 EP disclosed
WO-1982000295-A1 ABRASION RESISTANT ULTRAVIOLET LIGHT CURABLE HARD COATING COMPOSITIONS GEN ELECTRIC (US) 1982-02-04 WO disclosed