Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15725712 | 0.84 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL2735547 | 0.79 | — | — | |
| SCHEMBL6922236 | 0.79 | — | — | |
| SCHEMBL13906989 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRCASP1ALOX15L3MBTL1 | |
| SCHEMBL4278112 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TSHRCASP1L3MBTL1CHRNA7 | |
| SCHEMBL1878801 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRCASP1L3MBTL1CHRNA7 | |
| SCHEMBL1878800 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRCASP1L3MBTL1CHRNA7 | |
| SCHEMBL6922892 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRCASP1L3MBTL1CHRNA7 | |
| SCHEMBL22214361 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHRCASP1L3MBTL1 | |
| SCHEMBL4877698 | 0.70 | ALDH1A1 (1.00) | ALDH1A1TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9411226-B2 | Chemically amplified resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-08-09 | — | — | US | disclosed |
| US-9411226-B2 | Chemically amplified resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-08-09 | — | — | US | disclosed |
| EP-1414813-B1 | 1,2,4-TRIOXOLANE ANTIMALARIALS | MEDICINES MALARIA VENTURE MMV (CH) | 2006-09-13 | — | — | EP | disclosed |
| US-6906205-B2 | Spiro and dispiro 1,2,4-trioxolane antimalarials | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2005-06-14 | — | — | US | disclosed |
| US-20040186168-A1 | Such as spiroadamantane on one side and 4-substituted spiro-cyclohexyl on other side; structurally simple, nontoxic, easy synthesis, potent parasiticides | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2004-09-23 | — | — | US | disclosed |
| EP-1414813-A1 | 1,2,4-TRIOXOLANE ANTIMALARIALS | Medicines for Malaria Venture (CH) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003000676-A1 | 1,2,4-TRIOXOLANE ANTIMALARIALS | MEDICINES FOR MALARIA VENTURE (CH) | 2003-01-03 | — | — | WO | disclosed |
| US-6486199-B1 | Spiro and dispiro 1,2,4-trioxolane antimalarials | MEDICINES FOR MALARIA VENTURE MMV INTERNATIONAL CENTRE COINTRIN (CH) | 2002-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186168-A1 | Such as spiroadamantane on one side and 4-substituted spiro-cyclohexyl on other side; structurally simple, nontoxic, easy synthesis, potent parasiticides | DHODH, SQLE, SULT1E1 | ALDH1A1 135/4885TSHR 2043/4885CASP1 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.