Acrylamide

Acrylamide

SCHEMBL6037032

C=CC(N)=O.C=CC(N)=O.NCCNCCN

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
TSHR P16473 2/20 0.55
FGFR4 P22455 1/20 0.55
CA12 O43570 5/20 0.50
CA6 P23280 5/20 0.50
CA7 P43166 5/20 0.50
CA9 Q16790 5/20 0.50
CA14 Q9ULX7 5/20 0.50
CA5B Q9Y2D0 5/20 0.50
MEN1 O00255 2/20 0.50
RECQL P46063 2/20 0.50
KMT2A Q03164 2/20 0.50
CA2 P00918 4/20 0.48
CA4 P22748 4/20 0.48
CA5A P35218 4/20 0.48
CA3 P07451 3/20 0.48
ALOX15 P16050 3/20 0.48
LMNA P02545 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
CA1 P00915 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL27989513 1.00 ALDH1A1 (0.55) ALDH1A1TSHRFGFR4CA12CA6
Acrylamide SCHEMBL81627 1.00 ALDH1A1 (0.55) ALDH1A1TSHRFGFR4CA12CA6
Trientine SCHEMBL3247131 0.98 CA12 (0.52) ALDH1A1TSHRFGFR4CA12CA6
Trientine SCHEMBL731670 0.98 CA12 (0.52) ALDH1A1TSHRFGFR4CA12CA6
Acrylamide SCHEMBL28268675 0.98 CA12 (0.52) ALDH1A1TSHRFGFR4CA12CA6
Trientine SCHEMBL3255538 0.98 CA12 (0.52) ALDH1A1TSHRFGFR4CA12CA6
Acrylamide SCHEMBL27461457 0.91 ALDH1A1 (0.46) ALDH1A1TSHRFGFR4CA12CA6
Norspermidine SCHEMBL9615504 0.91 CA12 (0.52) ALDH1A1TSHRFGFR4CA12CA6
Spermine SCHEMBL25404718 0.89 CA12 (0.56) ALDH1A1TSHRFGFR4CA12CA6
Acrylic Acid SCHEMBL29838100 0.85 CA12 (0.50) ALDH1A1TSHRCA12CA6CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006010083-A2 BIODEGRADABLE NANOPARTICLES MOLECULAR THERAPEUTICS, INC. (US) 2006-01-26 WO disclosed
US-4647636-A VINYLAROMATIC-GLYCIDYL ACRYLATE INTERPOLYMER PROTECTIVE COLLOID, EMULSIO POLYMERIZATION ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-03-03 US disclosed