Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ME2 | P23368 | 1/20 | 0.33 |
| ▸ | ME1 | P48163 | 1/20 | 0.33 |
| ▸ | ME3 | Q16798 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398183 | 0.84 | TAAR1 (0.41) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL1551156 | 0.77 | TAAR1 (0.54) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL18886107 | 0.76 | TAAR1 (0.52) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL1125158 | 0.76 | TAAR1 (0.52) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL1501852 | 0.76 | TAAR1 (0.52) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL6442351 | 0.74 | TAAR1 (0.50) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL10606675 | 0.74 | TAAR1 (0.50) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL10382468 | 0.74 | TAAR1 (0.50) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL7159745 | 0.74 | TAAR1 (0.40) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL6745723 | 0.74 | MAOB (0.46) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052587-A1 | Racemoselective preparation of isolable ansa-metallocene biphenoxide complexes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052587-A1 | Racemoselective preparation of isolable ansa-metallocene biphenoxide complexes | ITPA, NBAS, ARSA | TAAR1 3230/4885MAPK1 2085/4885CYP2C19 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.