Tetrazole

Tetrazole

SCHEMBL6037735

O=P(O)(O)Oc1c[nH]c2ccc(Br)c(Cl)c12.c1nnn[nH]1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.34
HTR1A P08908 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrazole SCHEMBL735500 1.00 HTR2A (0.34) HTR2AHTR1AHTR2CHTR2B
Tetrazole SCHEMBL225087 1.00 HTR2A (0.34) HTR2AHTR1AHTR2CHTR2B
Tetrazole SCHEMBL526238 0.99 HTR2A (0.33) HTR2AHTR1AHTR2CHTR2B
Tetrazole SCHEMBL5145009 0.90 HTR2A (0.31) HTR2AHTR1AHTR2CHTR2B
O-Tolylamine SCHEMBL7116171 0.88 HTR2A (0.32) HTR2AHTR1AHTR2CHTR2B
SCHEMBL23488 0.88 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2B
SCHEMBL29356973 0.88 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2B
SCHEMBL5058499 0.86 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2B
Ammonia Solution, Strong SCHEMBL20492883 0.86 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2B
SCHEMBL17668115 0.86 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385757-B Method and kit for room temperature in situ detection of target nucleic acid in biological sample 塞雷公司 2020-04-03 CN disclosed
US-20060216761-A1 Isolation material for hormone disrupting substance, method of concentrating and method of clean-up JAPAN ENVIROCHEMICALS, LTD. (JP) 2006-09-28 US disclosed
US-20050136492-A1 Affinity labeling of enzymes for detection of enzyme activity level in living cells IMMUNOCHEMISTRY TECHNOLOGIES, LLC 2005-06-23 US disclosed
EP-1514597-A1 ISOLATION MATERIAL FOR HORMONE DISRUPTING SUBSTANCE, METHOD OF CONCENTRATING AND METHOD OF CLEAN-UP Japan Envirochemicals, Ltd. (JP) 2005-03-16 EP disclosed
US-20050019833-A1 Proteins capable of binding to environmental hormones and process for producing the same JAPAN ENVIROCHEMICALS, LTD. (JP) 2005-01-27 US disclosed
EP-1482043-A1 PROTEINS CAPABLE OF BINDING TO ENVIRONMENTAL HORMONES AND PROCESS FOR PRODUCING THE SAME Japan Envirochemicals, Ltd. (JP) 2004-12-01 EP disclosed
US-6720409-B2 USEFUL IN THE DIAGNOSIS AND TREATMENT OF INFLUENZA A VIRUS TAKARA SHUZO CO., LTD. (JP) 2004-04-13 US disclosed
WO-2003058194-A2 AFFINITY LABELING OF ENZYMES FOR DETECTION OF ENZYME ACTIVITY LEVEL IN LIVING CELLS IMMUNOCHEMISTRY TECHNOLOGIES, LLC (US) 2003-07-17 WO disclosed
US-20020054882-A1 Anti-human influenza virus antibody TAKARA BIO INC. (JP) 2002-05-09 US disclosed
EP-1003545-A4 HEPARIN-BINDING GROWTH FACTOR (HBGF) POLYPEPTIDES CHILDRENS HOSP RES FOUNDATION (US) 2002-03-06 EP disclosed
WO-1999007407-A1 HEPARIN-BINDING GROWTH FACTOR (HBGF) POLYPEPTIDES CHILDRENS HOSPITAL RESEARCH FOUNDATION (US) 1999-02-18 WO disclosed
WO-1997031268-A1 CHROMATOGRAPHIC STRIP HAVING DETECTION AND CONTROL ZONES ORIENTED PARALLEL TO THE DIRECTION OF FLOW UNIVERSAL HEALTHWATCH, INC. (US) 1997-08-28 WO disclosed
US-5631350-A Anti-human influenza virus antibody TAKARA SHUZO CO., LTD. (JP) 1997-05-20 US disclosed
US-5589174-A DIAGNOSIS AND TREATMENT OF INFLUENZA A VIRUS, VACCINE TAKARA SHUZO CO., LTD. (JP) 1996-12-31 US disclosed
EP-0621339-A2 Immunogenic human influenza A virus haemagglutinin polypeptides TAKARA SHUZO CO. LTD. (JP) 1994-10-26 EP disclosed
US-5075078-A SELF-PERFORMING IMMUNOCHROMATOGRAPHIC DEVICE ABBOTT LABORATORIES (US) 1991-12-24 US disclosed
EP-0429470-A1 ANTIBODY RECOGNITION OF FRAGMENTS FROM CYTOMEGALOVIRUS THE CHILDREN'S HOSPITAL, INCORPORATED (US) 1991-06-05 EP disclosed
WO-1990006771-A1 PROTEOLYTIC FRAGMENTS OBTAINED FROM HUMAN CYTOMEGALOVIRUS GLYCOPROTEIN COMPLEX I THE CHILDREN'S HOSPITAL, INCORPORATED (US) 1990-06-28 WO disclosed
WO-1990000062-A1 ANTIBODY RECOGNITION OF FRAGMENTS FROM CYTOMEGALOVIRUS THE CHILDREN'S HOSPITAL, INCORPORATED (US) 1990-01-11 WO disclosed
EP-0251527-A2 Haptenylated reagents and immunoassays Panab Laboratories, Inc. (US) 1988-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050019833-A1 Proteins capable of binding to environmental hormones and process for producing the same SHBG, SERPINA6, NR5A1 HTR2A 1853/4885HTR1A 2995/4885HTR2C 2914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.