Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | GLA | P06280 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | HBB | P68871 | 2/20 | 1.00 |
| ▸ | STAT6 | P42226 | 1/20 | 1.00 |
| ▸ | CHEK1 | O14757 | 1/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 1/20 | 1.00 |
| ▸ | ABCC4 | O15439 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | HNRNPA1 | P09651 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Camptothecin SCHEMBL29360250 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL29351099 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL788063 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL28057307 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL29369924 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL4304557 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL2298909 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL548833 | 0.99 | TOP1 (0.98) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL17112859 | 0.99 | TOP1 (0.98) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Camptothecin SCHEMBL3117386 | 0.99 | TOP1 (0.98) | TOP1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 119452 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144890-A1 | ANTIBODY DRUG CONJUGATE COMPRISING NMT INHIBITOR CONJUGATED TO AN ANTIBODY | MyricX Pharma Limited (GB) | 2026-05-28 | — | — | US | claimed |
| US-20260144882-A1 | ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF | BIO-THERA SOLUTIONS, LTD. (CN) | 2026-05-28 | — | — | US | claimed |
| EP-4748861-A1 | BISPECIFIC ANTIBODY, DRUG CONJUGATE THEREOF, AND USE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2026-05-27 | — | — | EP | claimed |
| EP-4747282-A1 | ACTIVATABLE TYROSINE-PROTEIN KINASE MEMBRANE RECEPTOR (ROR) ANTIBODY-DRUG CONJUGATES AND USES THEREOF | Exelixis, Inc. (US) | 2026-05-27 | — | — | EP | claimed |
| EP-4747283-A1 | TYROSINE-PROTEIN KINASE MEMBRANE RECEPTOR 1 (ROR1) ANTIBODY-DRUG CONJUGATES AND USES THEREOF | Exelixis, Inc. (US) | 2026-05-27 | — | — | EP | claimed |
| EP-4746922-A2 | INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2 ANTIBODY-DRUG CONJUGATES AND USES THEREOF | Exelixis, Inc. (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122080142-A | Polypeptide for cancer targeted therapy and corresponding drug/fluorescent dye conjugate thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080207-A | Antigen binding molecules, and drug conjugates and uses thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075733-A | Preparation method and application of linker medicine and antibody-medicine conjugate thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122070932-A | Application of combination of decitabine and anti-HER 2 antibody in preparation of medicines for treating tumors | 上海交通大学 | 2026-05-22 | — | — | CN | claimed |
| EP-0137145-B1 | NEW CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1988-04-27 | — | — | EP | claimed |
| US-RE32518-E | Camptothecin derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1987-10-13 | — | — | US | claimed |
| EP-0074256-B1 | CAMPTOTHECIN DERIVATIVES, PROCESSES FOR PREPARING SAME, FORMULATIONS CONTAINING SUCH DERIVATIVES AND THEIR USE | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1986-11-20 | — | — | EP | claimed |
| US-4604463-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1986-08-05 | — | — | US | claimed |
| EP-0137145-A1 | New camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1985-04-17 | — | — | EP | claimed |
| US-4473692-A | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1984-09-25 | — | — | US | claimed |
| EP-0088642-A2 | New camptothecin derivatives and process for their preparation | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1983-09-14 | — | — | EP | claimed |
| US-4399282-A | 7-HYDROXYALKYL DERIVATIVES USING FREE RADICAL CATALYSTS; ANTITUMOR AND -CARCINOGENIC AGENTS; NONTOXIC | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1983-08-16 | — | — | US | claimed |
| US-4399276-A | 7-Substituted camptothecin derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1983-08-16 | — | — | US | claimed |
| EP-0074256-A1 | Camptothecin derivatives, processes for preparing same, formulations containing such derivatives and their use | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1983-03-16 | — | — | EP | claimed |