Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904044 | 0.81 | CA1 (0.60) | SMN1; SMN2CA9CA1CA2CA4 | |
| SCHEMBL6038207 | 0.81 | LMNA (0.47) | LMNAHTTSMN1; SMN2CA9ALOX15 | |
| SCHEMBL6038197 | 0.81 | HDAC1 (0.56) | LMNAHTTSMN1; SMN2CA9ALOX15 | |
| SCHEMBL6038193 | 0.81 | HDAC1 (0.56) | LMNAHTTSMN1; SMN2CA9ALOX15 | |
| SCHEMBL8777049 | 0.80 | LMNA (0.72) | LMNAHTTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL6038182 | 0.78 | LMNA (0.68) | LMNAHTTSMN1; SMN2CA9ALOX15 | |
| SCHEMBL6037919 | 0.77 | HDAC1 (0.60) | LMNAHTTSMN1; SMN2CA9ALOX15 | |
| SCHEMBL6037922 | 0.77 | HDAC1 (0.60) | LMNAHTTSMN1; SMN2CA9ALOX15 | |
| SCHEMBL399122 | 0.76 | LMNA (0.77) | LMNAHTTSMN1; SMN2CA9ALOX15 | |
| SCHEMBL6038095 | 0.75 | LMNA (0.64) | LMNAHTTSMN1; SMN2ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | LMNA 851/4885HTT 846/4885SMN1; SMN2 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.