Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | AGXT | P21549 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360819 | 0.82 | NR4A2 (0.50) | IDO1AGXTNR4A2GRM5MAOB | |
| SCHEMBL5282539 | 0.81 | IDO1 (0.45) | IDO1AGXTNR4A2GRM5MAOB | |
| SCHEMBL5279148 | 0.81 | MAOB (0.51) | IDO1AGXTNR4A2GRM5MAOB | |
| SCHEMBL1170286 | 0.80 | TSHR (0.56) | GRM5ALDH1A1 | |
| SCHEMBL30984448 | 0.78 | GRM5 (0.43) | IDO1AGXTNR4A2GRM5MAOB | |
| SCHEMBL30984473 | 0.78 | GRM5 (0.43) | IDO1AGXTNR4A2GRM5MAOB | |
| SCHEMBL30984470 | 0.78 | PTPN1 (0.44) | IDO1AGXTNR4A2GRM5MAOB | |
| SCHEMBL7888039 | 0.76 | IDO1 (0.64) | IDO1AGXTNR4A2MAOBPARP10 | |
| SCHEMBL7501972 | 0.76 | MMP1 (0.49) | IDO1AGXTNR4A2MAOBPARP10 | |
| Hydroxyamine SCHEMBL8923579 | 0.74 | IDO1 (0.62) | IDO1AGXTNR4A2MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | IDO1 1132/4885AGXT 587/4885NR4A2 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.