Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 7/20 | 0.53 |
| ▸ | EDNRA | P25101 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 2/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038657 | 0.91 | CCR4 (0.54) | CCR4EDNRAALPLKMT2A | |
| SCHEMBL6038631 | 0.90 | CCR4 (0.58) | CCR4EDNRAALDH1A1SMN1; SMN2ALPL | |
| SCHEMBL6039138 | 0.90 | CCR4 (0.63) | CCR4EDNRAALPL | |
| SCHEMBL6038965 | 0.85 | CCR4 (0.68) | CCR4EDNRAALDH1A1 | |
| SCHEMBL6039091 | 0.85 | CCR4 (0.56) | CCR4EDNRAALPL | |
| SCHEMBL6038944 | 0.84 | SLC40A1 (0.50) | CCR4EDNRA | |
| SCHEMBL6039258 | 0.84 | CCR4 (0.62) | CCR4EDNRAMEN1KMT2A | |
| SCHEMBL6039125 | 0.84 | CCR4 (0.64) | CCR4EDNRAALPL | |
| SCHEMBL6039215 | 0.82 | CCR4 (0.61) | CCR4EDNRAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6038848 | 0.81 | EDNRA (0.57) | CCR4EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004010-A1 | Ccr4 antagonist and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1541563-A1 | CCR4 ANTAGONIST AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004010-A1 | Ccr4 antagonist and medical use thereof | CCR4, CCR1, CCR9 | CCR4 1/4885EDNRA 512/4885ALDH1A1 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.