Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11546503 | 1.00 | FAAH (0.48) | FAAHTRPV1F7F3TSHR | |
| SCHEMBL29357418 | 0.97 | — | — | |
| SCHEMBL55788 | 0.97 | — | — | |
| SCHEMBL55789 | 0.97 | — | — | |
| SCHEMBL2693101 | 0.93 | FAAH (0.48) | FAAHTRPV1F7F3TSHR | |
| SCHEMBL2693098 | 0.93 | FAAH (0.48) | FAAHTRPV1F7F3TSHR | |
| SCHEMBL860507 | 0.93 | FAAH (0.55) | FAAHTRPV1F7F3TERT | |
| SCHEMBL860506 | 0.93 | FAAH (0.55) | FAAHTRPV1F7F3TERT | |
| Hydrochloric Acid SCHEMBL8111971 | 0.93 | FAAH (0.48) | FAAHTRPV1F7F3TSHR | |
| Hydrochloric Acid SCHEMBL29967611 | 0.93 | FAAH (0.48) | FAAHTRPV1F7F3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7130107-B2 | Method of preparing encapsulated bichromal balls | XEROX CORPORATION (US) | 2006-10-31 | — | — | US | disclosed |
| US-20060119926-A1 | Method of preparing encapsulated bichromal balls | XEROX CORPORATION | 2006-06-08 | — | — | US | disclosed |
| US-7038833-B1 | Encapsulated bichromal balls | XEROX CORPORATION (US) | 2006-05-02 | — | — | US | disclosed |
| US-6492025-B1 | Microcapsule composition | XEROX CORPORATION | 2002-12-10 | — | — | US | disclosed |
| US-6488870-B1 | Encapsulation process | XEROX CORPORATION | 2002-12-03 | — | — | US | disclosed |
| EP-1219348-A2 | Encapsulation process | Xerox Corporation (US) | 2002-07-03 | — | — | EP | disclosed |
| US-6110444-A | DISPERSION FREE MICROBUBBLES OF WATER INSOLUBLE GAS | NYCOMED IMAGING AS (GB) | 2000-08-29 | — | — | US | disclosed |
| EP-0748227-A1 | GAS-CONTAINING MICROCAPSULES USEFUL AS CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | NYCOMED IMAGING AS (NO) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023615-A1 | GAS-CONTAINING MICROCAPSULES USEFUL AS CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | HOLMES, MICHAEL, JOHN (GB) | 1995-09-08 | — | — | WO | disclosed |
| US-4170601-A | SELECTIVELY FORMING INCLUSION COMPLEX WITH UREA | LEADBETTER GRAHAM | 1979-10-09 | — | — | US | disclosed |