SCHEMBL6038433

SCHEMBL6038433

CCCCOC(=O)c1ccccc1C(=O)OC(=O)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.76
TDP1 Q9NUW8 4/20 0.76
L3MBTL1 Q9Y468 3/20 0.76
MAPK1 P28482 4/20 0.69
CYP3A4 P08684 3/20 0.69
TP53 P04637 1/20 0.69
ALDH1A1 P00352 6/20 0.67
LMNA P02545 4/20 0.67
HSD17B10 Q99714 2/20 0.61
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
CYP1A2 P05177 2/20 0.54
CYP2C19 P33261 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
ESR1 P03372 1/20 0.54
CYP2D6 P10635 1/20 0.54
NR1H2 P55055 1/20 0.54
RNASEL Q05823 1/20 0.54
CYP2C9 P11712 1/20 0.53
PDE4D Q08499 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28564455 0.91 ALDH1A1 (0.74) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL28471364 0.89 TSHR (0.78) TSHRTDP1L3MBTL1MAPK1CYP3A4
Dibutyl Phthalate SCHEMBL27468448 0.89 TSHR (0.78) TSHRTDP1L3MBTL1MAPK1CYP3A4
Dibutyl Phthalate SCHEMBL28924279 0.89 TSHR (0.96) TSHRTDP1L3MBTL1MAPK1CYP3A4
Dibutyl Phthalate SCHEMBL8813340 0.89 TSHR (0.96) TSHRTDP1L3MBTL1MAPK1CYP3A4
Dibutyl Phthalate SCHEMBL15766379 0.88 TSHR (0.81) TSHRTDP1L3MBTL1MAPK1CYP3A4
Dibutyl Phthalate SCHEMBL27974397 0.88 TSHR (0.81) TSHRTDP1L3MBTL1MAPK1CYP3A4
Dibutyl Phthalate SCHEMBL27657051 0.88 TSHR (0.81) TSHRTDP1L3MBTL1MAPK1CYP3A4
Dibutyl Phthalate SCHEMBL29353340 0.87 TSHR (1.00) TSHRTDP1L3MBTL1MAPK1CYP3A4
Dibutyl Phthalate SCHEMBL2330224 0.87 TSHR (1.00) TSHRTDP1L3MBTL1MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10658091-B1 Ceramic electrical insulation coating The Florida State University Research Foundation, Inc. (US) 2020-05-19 US claimed
WO-2024181671-A1 ADHESIVE COMPOSITION AND ADHESIVE SHEET FORMED THEREFROM 동우화인켐 주식회사 2024-09-06 WO disclosed
US-10658091-B1 Ceramic electrical insulation coating The Florida State University Research Foundation, Inc. (US) 2020-05-19 US disclosed
US-7078091-B2 Membranes of polyurethane based materials including polyester polyols NIKE, INC. (US) 2006-07-18 US disclosed
EP-1498257-A1 Membranes of polyurethane based materials including polyester polyols NIKE INTERNATIONAL LTD (US) 2005-01-19 EP disclosed
US-20040195174-A1 Membranes of polyurethane based materials including polyester polyols BONK HENRY W (US) 2004-10-07 US disclosed
US-6797215-B2 GAS TRANSMISSION RATE OF 15.0 OR LESS FOR NITROGEN GAS WHEREIN SAID MEMBRANE HAS AN AVERAGE THICKNESS OF APPROXIMATELY 20.0 MILS. NIKE, INC. 2004-09-28 US disclosed
EP-0884960-B1 INFLATED CLOSED CONTAINERS MADE OF POLYESTERURETHANE BASED MEMBRANES AND THEIR MANUFACTURING METHOD NIKE INTERNATIONAL LTD (US) 2004-08-18 EP disclosed
US-6692803-B2 GAS TRANSMISSION RATE OF 15.0 OR LESS FOR NITROGEN GAS AND AN AVERAGE THICKNESS OF APPROXIMATELY 20.0 MILS. NIKE, INC. 2004-02-17 US disclosed
US-6652940-B2 Membrane including a polyesterurethane copolymer, the membrane having low nitrogen gas transmission rate and given thickness; variety of end-uses, such as fuel lines, in-line skate wheels, cushioning in prosthetics; containers NIKE, INC. 2003-11-25 US disclosed
US-6013340-A MEMBRANES WHICH, UNDER CERTAIN EMBODIMENTS, SERVE TO SELECTIVELY CONTROL THE DIFFUSION OF GASES THROUGH THE MEMBRANE; CUSHIONING DEVICES USEFUL IN FOOTWEAR NIKE, INC. (US) 2000-01-11 US disclosed
EP-0884960-A4 MEMBRANES OF POLYURETHANE BASED MATERIALS INCLUDING POLYESTER POLYOLS NIKE INTERNATIONAL LTD (US) 1999-12-22 EP disclosed
CN-1206211-A Key pad and its manufacturing method ALFA GIKEN CO LTD (JP) 1999-01-27 CN disclosed
EP-0884960-A1 MEMBRANES OF POLYURETHANE BASED MATERIALS INCLUDING POLYESTER POLYOLS NIKE INTERNATIONAL LTD (US) 1998-12-23 EP disclosed
WO-1996039885-A1 MEMBRANES OF POLYURETHANE BASED MATERIALS INCLUDING POLYESTER POLYOLS NIKE, INC. (US) 1996-12-19 WO disclosed
US-4716213-A FOAMS AND RIGID ELASTOMERS CENTRE DE RECHERCHE INDUSTRIELLE DU QUEBEC (CA) 1987-12-29 US disclosed
US-4525574-A Polyesters polyols prepared from glutaric acid, succinic acid and adipic acid, and polyurethanes prepared therefrom CENTRE DE RECHERCHE INDUSTRIELLE DE QUEBEC (CA) 1985-06-25 US disclosed
US-4249953-A SMALL PARTICLE SIZE BAYER AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4126727-A Resinous polymer sheet materials having selective, decorative effects CONGOLEUM CORPORATION (US) 1978-11-21 US disclosed
US-4089819-A Process of preparing vesiculated polyester resin granules DULUX AUSTRALIA LIMITED (AU) 1978-05-16 US disclosed